Next to Vatnajökull, the largest glacier in Europe (8000 km2), and in the foothills of Hvannadalshnjúkur, the highest point of the country (2111 m), lies Fosshotel Glacier Lagoon which opened in 2016 and it seems like they got everythig just right.
A 4-star cosyness of modern design, comfortable rooms and efficient staff. And yes, 20 min to the west is Skaftafell, and 20 min to the east is Jökulsárlón. If those names do do not ring a bell, you should do some research, that is, if you are planning to spend any amount of time in Iceland at all.
It may look like you have arrived at the end of the world. Whether you are coming from the west across black volcanic sands licked by dirty glacier tongues or from the east where the breathtaking beauty of the Glacier Lagoon marries the sea and the sky in a symphony of prehistoric wilderness, you will know that you have been somewhere worth having been. And this save haven overlooking a land at the mercy of ice and fire is so where you want to spend the night either facing the mountain trying to spot the aurora or looking out towards the North Atlantic trying to write poetry.
This hotel is in the right place at the right time whenever you arrive.